A Research on Synthesis of Oxazine Derivatives & Screening of Oxazine Derivatives for Certain Pharmacological Activities

Oxazine derivatives are an important class of heterocycles, which has attracted much synthetic interest due to their wide range of biological activities. Oxazine is a heterocyclic compound can be formally derived from benzene, and its reduction products, by suitable substitution of carbon (and hydrogen) atoms by nitrogen and oxygen. In the last few years oxazine derivatives have proved to be valuable synthetic intermediates and also possess important biological activities like sedative, analgesic, antipyretic, anticonvulsant, antitubercular, antitumour, antimalarial and antimicrobial. In these days, development of drug resistance is a major problem and to overcome this situation, it is necessary to synthesize new classes of compounds. Mathew George 1 , Lincy Joseph 2 , Hithin Raj.Sadanandan 2* 1 Department of Pharmacology, Pushpagiri College of Pharmacy, Thiruvalla-689107, Kerala, India 2 Department of Pharmaceutical chemistry, Pushpagiri College of Pharmacy, Thiruvalla-689107, Kerala, India. Submission: 29 May 2016 Accepted: 3 June 2016 Published: 25 June 2016 www.ijppr.humanjournals.com Citation: Hithin Raj.Sadanandan et al. Ijppr.Human, 2016; Vol. 6 (3): 14-42. 15